The development of cancer in individuals results from the interaction of three factors:
– Genetics (genes)
– Lifestyle (diet, exercise, etc.)
– Environment (air and water quality, stress in life)
The results of the test allow for early detection of hereditary cancer risk:
Support consultations with geneticists and oncologists and free testing for three close relatives.
(*) Source: Statistics adapted from the American Cancer Society’s publication, Cancer Facts & Figures 2020, the ACS website, and the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program (all sources accessed January 2020)
oncoSure Plus is a package of screening tests for 133 genes associated with 30 common hereditary cancers.
Including:
No | Genetic mutations associated with hereditary cancer | Testing genes |
---|---|---|
01 | Skin Cancer | BAP1, BRAF, BRCA2, CBL, CDK4, CDKN2A, CYLD, DDB2, DKC1, ERCC2, ERCC3, ERCC4, ERCC5, FH, FLCN, HNF1A, KITLG, MAP2K1, MAP2K2, MITF, NRAS, POLH, PTCH1, PTEN, RECQL4, TINF2, TP53, WRN, XPA, XPC |
02 | Acute Leukemia (blood cancer) | ANKRD26, BUB1B, CBL, CEBPA, CEP57, EGFR, ELANE, ETV6, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, GATA2, NRAS, PAX5, PDGFRA, PRF1, PTPN11, RUNX1, SPRED1, SRP72, WT1 |
03 | Colorectal Cancer | APC, AXIN2, BLM, BMPR1A, CBL, CDH1, CHEK2, DKC1, EPCAM, EXO1, GREM1, MLH1, MLH3, MSH2, MSH6, MUTYH, NRAS, NTHL1, PMS1, PMS2, POLD1, PTEN, SMAD4, SOS1, STK11, TP53 |
04 | Breast Cancer | ATM, BARD1, BLM, BRCA1, BRCA2, CDH1, CHEK2, DKC1, MRE11A, NBN, NF1, PALB2, PMS1, PPM1D, PTEN, RAD50, SHOC2, SLX4, STK11, TP53, XRCC2 |
05 | Lung Cancer | BRAF, DICER1, DKC1, EGFR, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, FLCN, KRAS, MAP2K1, MAP2K2, NRAS, RET, SMARCA4, SOS1, TERC, TERT |
06 | Kidney Cancer | BAP1, BUB1B, CDKN1C, CEP57, DICER1, DIS3L2, EPCAM, FH, HNF1A, MET, MLH1, MSH2, MSH6, PMS2, SDHB, VHL, WT1 |
07 | Pancreatic Cancer | APC, BMPR1A, BRCA1, BRCA2, CDK4, CDKN2A, DKC1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, SMAD4, STK11, TP53 |
08 | Ovarian Cancer | BRCA1, BRCA2, BRIP1, DICER1, EPCAM, ERCC1, MLH1, MRE11A, MSH2, MSH6, MUTYH, PALB2, PMS2, RAD51C, STK11, TP53 |
09 | Stomach Cancer | APC, BMPR1A, CDH1, EPCAM, KIT, MLH1, MSH2, MSH6, NSUN2, PMS2, PTEN, SMAD4, STK11, TP53 |
10 | Bladder Cancer | ATM, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, HRAS, RAF1 |
11 | Endometrial Cancer | CBL, CDKN1C, EPCAM, FH, MLH1, MLH3, MSH2, MSH6, PMS2, PTEN, STK11, TP53 |
12 | Prostate Cancer | BRCA1, BRCA2, EPCAM, EZH2, HOXB13, MLH1, MSH2, MSH6, PALB2, PMS2, TP53 |
13 | Head and Neck Cancer | FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM |
14 | Brain Cancer | ERCC2, ERCC3, ERCC4, ERCC5, NF1, NSD1, PHOX2B, SUFU |
15 | Neural Paraganglioma | RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, VHL |
16 | Biliary Tract Cancer | BAP1, BRAF, KRAS, NRAS, TSC1, TSC2 |
17 | Thyroid Cancer | CDKN1C, DICER1, RET, TINF2, WRN |
18 | Bone Cancer | EXT1, EXT2, RECQL4, SMARCB1 |
19 | Multiple Endocrine Neoplasias | CDKN1B, MEN1, PRKAR1A, RET |
20 | Sarcoma | BUB1B, CEP57, HRAS |
21 | Liver Cancer | GPC3, HNF1A |
22 | Small Bowel Cancer | BMPR1A, KIT |
23 | Pituitary Tumor | AIP, DKC1 |
24 | Neuroblastoma | ALK, HRAS |
25 | Nerve Fibroma | NF1, NF2 |
26 | Adrenal Myeloma | MAX, RET, TMEM127 |
27 | Parathyroid Cancer | CDC73 |
28 | Retinoblastoma | RB1 |
29 | Esophageal Cancer | RHBDF2 |
30 | Multiple Myeloma | BRAF |
American Society of Clinical Oncology
American Cancer Society
National Comprehensive Cancer Network
Ministry of Health
Detects mutations in family-inherited genes that increase the risk of common types of cancer. The test results help you evaluate the probability that you will have certain cancers for yourself and your family.
Next-generation sequencing technology (Illumina) from the United States was developed by Vietnam’s leading medical advisors and a team of professionals. In only 14 days, a high-quality lab that complies with ISO standards will provide you with more than 99-percent-correct test results.
The team of experts and geneticists at Gene Solutions are always available to accompany you before and after each test and provide recommendations based on the results.
The USA standard DNA sampling kit, which allows you to collect samples at home in less than a minute, is painless and incredibly convenient.
The results assist in tracking cancer/chronic disease progression and planning effective interventions. In addition, it is possible to improve the efficacy of treatment by choosing an appropriate regimen.
If the initial test identifies a mutation, three family members will receive free testing. Take the initiative to prevent and protect your family’s health.
(*) Source: National Institutes of Health.
Pre-test counseling
Blood collection and extracellular DNA separation
Extracellular DNA sequencing
Results return and post-test counseling
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